Significance of findings: The authors report coordination mechanisms between oscillations recorded in the CA1 subfield of the hippocampus, prefrontal cortex, and olfactory bulb and cell ensemble activity in CA1 and prefrontal cortex during odor-cued decision-making. The important findings support the hypothesis that the β rhythm plays a role in coordinating CA1-prefrontal cortex ensembles during decision-making. Sensory-guided decision-making is of broad significance to many readers who are studying executive functions and decision-making behaviors, and the observations reported in this manuscript provide convincing evidence of mechanisms that may support these functions and behaviors.
“Rhythmic coordination and ensemble dynamics in the hippocampal-prefrontal network during odor-place associative memory and decision making”. Claire A Symanski, John H Bladon, Emi T Kullberg, Paul Miller, Shantanu P Jadhav. eLife 2022, 11:e79545. DOI: 10.7554/eLife.79545
Science at Brandeis 